ANTIOXIDANT ACTIVITY OF VARIOUS EXTRACTS OF JARAK TINTIR (Jatropha multifida L.) STEM, PHENOLIC AND FLAVONOID CONTENT

Authors

  • Akhirul Kahfi Syam Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia
  • Ari Sri Windyaswari epartment of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Jenderal Achmad Yani, Indonesia
  • Julia Ratnawati Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Jenderal Achmad Yani, Indonesia

DOI:

https://doi.org/10.70410/jfg.v7i3.182

Keywords:

Antioxidant, DPPH, Jatropha multifida L., phenolic, flavonoid

Abstract

Background: Jarak tintir (Jatropha multifida L.) was identified as one of family Euphorbiaceae and used by Indonesian people as traditional medicine.  This study aimed to measure IC50 of inhibition DPPH as free radicals and make statistical analysis of flavonoid and phenolic content and correlation with their IC50 of free radicals. Methods: Hot continuous extraction was done with Soxhlet apparatus using various polarity solvents (n-hexane, ethyl acetate, and methanol). Results: Methanol extract had the lowest IC50 32.26 ± 0.37 µg/mL of DPPH inhibition activity. Ethyl acetate extract had highest phenolic and highest flavonoid content with 35.21 ± 1.50 mg TAE/g extract and 49.41 ± 1.65 mg QE/g extract. Conclusion: Flavonoid and phenolic content in extracts had linier correlation with their IC50 of inhibition free radicals.

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Published

2020-12-07

How to Cite

Syam, A. K., Windyaswari, A. S. ., & Ratnawati, J. (2020). ANTIOXIDANT ACTIVITY OF VARIOUS EXTRACTS OF JARAK TINTIR (Jatropha multifida L.) STEM, PHENOLIC AND FLAVONOID CONTENT. JURNAL FARMASI GALENIKA, 7(3), 154–164. https://doi.org/10.70410/jfg.v7i3.182

Issue

Vol. 7 No. 3 (2020): Jurnal Farmasi Galenika Vol 7 No 3

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Artikel

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