ANTIHYPERGLICEMIA ACTIVITY OF WATER FRACTION, ETHYL ACETATE FRACTION, AND N- HEXANE FRACTION OF SPINACH LEAVES EXTRACT (Amaranthus Cruentus L) ON MALE MICE SWISS

Authors

  • Tita Nofianti School of Pharmacy, STIKes Bakti Tunas Husada Tasikmalaya, Cilolohan street no 36 Tasikmalaya, Indonesia, Indonesia

Keywords:

Spinach leaves, Amaranthus cruentus L., antihyperglicemia

Abstract

The activity test ofthe water fraction, ethyl acetate and n-hexane fraction of spinach leaves (Amaranthus cruentus L) has been conducted using the glucose tolerance method on male mice Swiss webster strain. The dose were water fraction 0.086 g/kg bw, ethyl acetate fraction 0.03g/kg body weight and n-hexane fraction 0.055 g/kg bw. Time measurement of blood glucose levels was conducted every 30 minutes for 120 minutes using a glucometer. The results showed that administration of water fraction, ethyl acetate fraction and n-hexane fraction of spinach leaves can lowering the blood glucose level of white male mice. While the best group that lowering the blood glucose level was ethyl acetate fraction 0,03 g/kg bw when compared to water fraction and n-hexane fraction. It can be concluded that spinach leaves showed antihyperglicemia.

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Published

2017-03-21

How to Cite

Nofianti, T. (2017). ANTIHYPERGLICEMIA ACTIVITY OF WATER FRACTION, ETHYL ACETATE FRACTION, AND N- HEXANE FRACTION OF SPINACH LEAVES EXTRACT (Amaranthus Cruentus L) ON MALE MICE SWISS. JURNAL FARMASI GALENIKA, 2(02). Retrieved from https://journal.bku.ac.id/jfg/index.php/jfg/article/view/36

Issue

Vol. 2 No. 02 (2015): JURNAL FARMASI GALENIKA

Section

Artikel

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