Development Of Pharmaceutical Material: Influence Of Drying Temperature Variation On Physical Characteristics Of Dry Chayote Powder

Authors

  • Patihul Husni Departemen Farmasetika dan Teknologi Farmasi, Fakultas Farmasi, Universitas Padjadjaran, Indonesia
  • Sussy Tryani Sutisna Putri Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Al-Ghifari, Indonesia
  • Irma Erika Herawati Program Studi Pendidikan Profesi Apoteker, Sekolah Tinggi Farmasi Indonesia, Indonesia
  • Mikhania Christiningtyas Eryani Fakultas Farmasi, Universitas Jember, Indonesia

DOI:

https://doi.org/10.70410/jfg.v11i3.357

Keywords:

Chayote, Sechium edule

Abstract

Chayote (Sechium edule (Jacq). Swartz) is potential to be a pharmaceutical material.  Therefore, this study aimed to determine the effect of drying temperature variations on the physical properties of dry chayote powder. The temperatures used in the drying process are 100 ºC, 80 ºC, and 60 ºC. Evaluation of dry chayote powder includes organoleptic test, water content, flow time, angle of repose, compressibility index, and particle size distribution. The results showed brown powder in color with a distinctive aromatic odor and sweet taste, 2.50-2.80% of water content, 5-6 second in flow time showing good flow properties, 32.21-33.42 º in angle of repose showing powder easy to flow, and compressibility index of 10% -18%. The particle size distribution of dry chayote powder was fine powder with particle size around 0.5-0.7 mm. Statistical analysis results showed there were no significant effect of the drying temperature variations on the physical properties of dry chayote powder. The conclusion of this study is drying temperature variations (100 ºC, 80 ºC, dan 60 ºC) does not affect the physical properties of dry chayote powder.

Downloads

Download data is not yet available.

References

Abrantes, C. G., Duarte, D. & Reis, C. P. 2016. An overview of pharmaceutical excipients: safe or not safe? Journal of pharmaceutical sciences, 105, 2019-2026.

Adhayanti, I. & Ahmad, T. 2020. Karakter mutu fisik dan kimia serbuk minuman instan kulit buah naga yang diproduksi dengan metode pengeringan yang berbeda. Media Farmasi, 16, 57-64.

Adhayanti, I. & Ahmad, T. 2021. Pengaruh metode pengeringan terhadap karakter mutu fisik dan kimia serbuk minuman instan kulit buah naga. Media Farmasi, 16, 57-64.

Baroyi, S. A. H. M., Abel, S. E. R., Al-Awaadh, A. M., Fikry, M., Shah, N. N. A. K., Salleh, F. S. M., Garg, V., Deng, T. & Yusof, Y. A. 2024. Sweet flow: exploring the flowability, caking, morphology, and solubility of date sugars as promising sugar substitutes. Powder Technology, 119925.

Chaudhari, S. P. & Patil, P. S. 2012. Pharmaceutical excipients: a review. Int J Adv Pharm Biol Chem, 1, 21-34.

Fu, A., Wang, Q., Mu, J., Ma, L., Wen, C., Zhao, X., Gao, L., Li, J., Shi, K. & Wang, Y. 2021. Combined genomic, transcriptomic, and metabolomic analyses provide insights into chayote (Sechium edule) evolution and fruit development. Horticulture Research, 8.

Hariadi, H., Wahyono, T., Darniadi, S., Maulana, H., Nurhadi, B., Amien, S., Karuniawan, A., Khan, A. A., Aziz, T. & Alasmari, A. F. 2024. Effect of maltodextrin concentration and drying temperature on the physicochemical characteristics of Sacha inchi (Plukenetia volubilis) extract powder. Italian Journal of Food Science, 36, 74-82.

Husni, P., Ikhrom, U. K. & Hasanah, U. 2021. Uji dan Karakterisasi Serbuk Pektin dari Albedo Durian sebagai Kandidat Eksipien Farmasi. Majalah Farmasetika, 6, 202-212.

Jannah, R. N., Fadraersada, J., Meylina, L. & Ramadhan, A. M. Formulasi Granul Antioksidan Ekstrak Etanol Daun Sirsak (Anonna muricata Linn.) Menggunakan Metode Granulasi Basah. Proceeding of Mulawarman Pharmaceuticals Conferences, 2018. 97-103.

Kudo, Y., Yasuda, M. & Matsusaka, S. 2020. Effect of particle size distribution on flowability of granulated lactose. Advanced Powder Technology, 31, 121-127.

Kurniati, D. E., Ardana, M. & Rusli, R. Formulasi sediaan tablet parasetamol dengan pati buah sukun (artocarpus communis) sebagai pengisi. Proceeding of Mulawarman Pharmaceuticals Conferences, 2017. 88-99.

Lynatra, C., Wardiyah, W. & Elisya, Y. 2019. Formulation of effervescent tablet of temulawak extract (Curcuma xanthorrhiza Roxb.) with variation of stevia as sweetener. SANITAS: Jurnal Teknologi dan Seni Kesehatan, 9, 1-11.

Madrigal-Santillán, E., Portillo-Reyes, J., Morales-González, J. A., Garcia-Melo, L. F., Serra-Pérez, E., Vidovi?, K., Sánchez-Gutiérrez, M., Álvarez-González, I. & Madrigal-Bujaidar, E. 2024. Evaluation of the Antigenotoxic Potential of Two Types of Chayote (Sechium edule) Juices. Plants, 13, 2132.

Muaja, A. D., Koleangan, H. S. & Runtuwene, M. R. 2013. Uji toksisitas dengan metode BSLT dan analisis kandungan fitokimia ekstrak daun soyogik (Saurauia bracteosa DC) dengan metode soxhletasi. Jurnal MIPA, 2, 115-118.

Raufovna, D. Z., Gulnora, R., Khurshidovna, M. F., Abbaskhanovna, A. N. & Oigul, R. 2024. MODERN EXCIPIENTS IN THE PRODUCTION OF TABLETS. Eurasian Journal of Medical Natural Sciences, 4, 188-198.

Rivera-Ponce, E. A., Arévalo-Galarza, M. d. L., Cadena-Iñiguez, J., Soto-Hernández, M., Ramírez-Rodas, Y. & García-Osorio, C. 2024. Characteristics and Potential Use of Fruits from Different Varietal Groups of Sechium edule (Jacq.) Sw. Horticulturae, 10, 844.

Rumaseuw, E. S. & Aritonang, F. 2021. UJI KADAR AIR JAMU SERBUK PENURUN BERAT BADAN YANG BEREDAR DI E-MARKETPLACE. Jurnal Kesehatan, 9, 23-33.

Swetha, S. G., Mekala, S., Metta, S., Madhavaram, K. & Meesala, S. 2024. An Exploration of Features of Excipient Selection in the Formulation of Semi-Solid Dosage Forms: A Comprehensive Review. African Journal of Pharmaceutical Sciences 4, 60-88.

Veigas, G. J., Bhattacharjee, A., Hegde, K. & Shabaraya, A. R. 2020. A brief review on Sechium edule. IJPSRR, 65, 165-168.

Vieira, E. F., Pinho, O., Ferreira, I. M. & Delerue-Matos, C. 2019. Chayote (Sechium edule): A review of nutritional composition, bioactivities and potential applications. Food chemistry, 275, 557-568.

Virtanen, S., Antikainen, O., Räikkönen, H. & Yliruusi, J. 2010. Granule size distribution of tablets. Journal of pharmaceutical sciences, 99, 2061-2069.

Wijayati, M., Saptarini, N. M., Herawati, I. E. & Suherman, S. E. 2014. Formulasi granul effervescent sari kering lidah buaya sebagai makanan tambahan. Indonesian Journal of Pharmaceutical Science and Technology, 1, 1-6.

Yanti, S. & Saputri, D. S. 2019. Uji aktivitas antioksidan serbuk ekstrak belimbing wuluh (Averrhoa blimbi L.). Jurnal Tambora, 3, 16-26.

Downloads

Published

2024-12-27

How to Cite

Husni, P., Tryani Sutisna Putri, S., Erika Herawati, I., & Christiningtyas Eryani, M. (2024). Development Of Pharmaceutical Material: Influence Of Drying Temperature Variation On Physical Characteristics Of Dry Chayote Powder . JURNAL FARMASI GALENIKA, 11(3), 190–202. https://doi.org/10.70410/jfg.v11i3.357

Citation Check