UJI TOKSISITAS EKSTRAK AIR SAGA POHON (Adenanthera pavonina L.) DENGAN METODE BRINE SHRIMP LETHALITY BIOASSAY (BSLB)

Authors

  • Quinzheilla Putri Arnanda Universitas Padjadjaran, Indonesia
  • Shinta Lestari Universitas Padjadjaran, Indonesia
  • Saqila Alifa Ramadhan Universitas Padjadjaran, Indonesia
  • Diah Siti Fatimah Universitas Padjadjaran, Indonesia
  • Shella Widiyastuti Universitas Padjadjaran, Indonesia
  • Dede Jihan Oktaviani Universitas Padjadjaran, Indonesia
  • Sandra Megantara Universitas Padjadjaran, Indonesia

DOI:

https://doi.org/10.70410/jfg.v7i2.168

Abstract

Ekstrak air saga pohon (Adenanthera pavonina L.) banyak digunakan dalam pengobatan antiinflamasi dan analgesik, namun masih belum diketahui toksisitasnya. Kandungan kimia dari daun saga pohon adalah alkaloid, triterpen, sterol, asam lemak, flavonoid, dan pavonin. Penelitian ini bertujuan untuk mengetahui toksisitas ekstrak air saga pohon menggunakan metode Brine Shrimp Lethality Bioassay (BSLB) dengan konsentrasi ekstrak 15.625; 31.25; 62.5; 125; 250; 500 dan 1000 g/ml yang dilakukan terhadap larva udang (Artemia salina Leach) menggunakan teknik microwell. Diperoleh hasil yaitu tidak ditemukan kematian larva udang di berbagai konsentrasi, sehingga dapat dikatakan ekstrak air saga pohon tidak bersifat toksik dan aman digunakan untuk pengobatan reumatik dan asam urat.

Kata kunci: Adenanthera pavonina L., BSLB, LC50, toksisitas.

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Published

2020-08-01

How to Cite

Arnanda, Q. P., Lestari, S., Ramadhan, S. A., Fatimah, D. S., Widiyastuti, S., Oktaviani, D. J., & Megantara, S. (2020). UJI TOKSISITAS EKSTRAK AIR SAGA POHON (Adenanthera pavonina L.) DENGAN METODE BRINE SHRIMP LETHALITY BIOASSAY (BSLB). JURNAL FARMASI GALENIKA, 7(2), 83–90. https://doi.org/10.70410/jfg.v7i2.168

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Vol. 7 No. 2 (2020): Jurnal Farmasi Galenika Volume 7 No. 2

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